Hidden Agenda - The Involvement of Endoplasmic Reticulum Stress and Unfolded Protein Response in Inflammation-Induced Muscle Wasting
Critically ill patients at the intensive care unit (ICU) often develop a generalized weakness, called ICU-acquired weakness (ICUAW).A major contributor to ICUAW is muscle atrophy, a loss of skeletal muscle mass and function.Skeletal muscle assures almost all of the vital functions of our body.It adapts rapidly in response to physiological as well a